Neuromodulators, such as Botox, and dermal fillers are both injectable cosmetic treatments that are used to improve the appearance of the skin. However, they work in different ways and are used to treat different types of concerns.Neuromodulators - Botox, Xeomin, Dysport - are made from a purified form of botulinum toxin. When injected into the skin, they work by temporarily paralyzing the muscles that cause wrinkles, resulting in a smoother, more youthful appearance. They are typically used to treat wrinkles and fine lines on the forehead, between the eyebrows, and around the eyes.Dermal fillers - Restlyane, Juvederm, Versa, Radiesse - on the other hand, are made from a variety of different substances, including hyaluronic acid, calcium hydroxylapatite, and poly-L-lactic acid. When injected into the skin, these substances add volume and fullness, smoothing out wrinkles and fine lines. They can also be used to add volume to the cheeks and lips, and to enhance the contours of the face.In general, neuromodulators and dermal fillers are both safe and effective treatments that can help to improve the appearance of the skin. The choice of treatment will depend on the individual's specific needs and goals, as well as the recommendation of a qualified medical professional.